First commercial single point confocal

[Guy Cox]

Search the CONFOCAL archive at http://listserv.acsu.buffalo.edu/cgi-bin/wa?S1=confocal

Yes, it's a pity that Kjell hasn't written an historical memoir

like the one Brad Amos wrote (recently cited in this thread).

It must have been neck and neck between Bio-Rad and

Sarastro for the first commercial sale of a single point

beam scanner.  The first published account of a 'beam

scanner' goes back to many years earlier but it worked

by displacing the objective, which I'd regard as cheating!

(Sorry, I'm not in my office and don't have the reference to

hand.)

 

                                                                    Guy

 

Optical Imaging Techniques in Cell Biology
by Guy Cox    CRC Press / Taylor & Francis

     http://www.guycox.com/optical.htm
______________________________________________
Associate Professor Guy Cox, MA, DPhil(Oxon)
Electron Microscope Unit, Madsen Building F09,
University of Sydney, NSW 2006
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---

From: Confocal Microscopy List on behalf of Eric Scarfone
Sent: Thu 15/11/2007 8:30 PM
To: [hidden email]
Subject: Re: First commercial single point confocal

Search the CONFOCAL archive at
http://listserv.acsu.buffalo.edu/cgi-bin/wa?S1=confocal

Dear all,
It would be really nice to have the whole inside story straightened up
someday!
A clear distinction should be made also between stage-scanning and
beam-scanning. In this respect which was the fisrt beam-scanner?

Concerning Sarastro, since I am now located in Sweden I contacted Kjell
Carlsson couldn't recall. Niels Alsund, then president of Sarastro, says
that the commercial company was founded in 1986 and sold its first set
up the same year here at the Karolinska Institutet. The prototype
however was running before that (probably at KTH where Kjell worked?)
but I got no dates on that!
Best Whishes to all.
Eric

Eric Scarfone, PhD, CNRS,
Center for Hearing and communication Research
Department of Clinical Neuroscience
Karolinska Institutet

Postal Address:
CFH, M1:02
Karolinska Hospital,
SE-171 76 Stockholm, Sweden

Work:  [phone],
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email:  [hidden email]
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----- Original Message -----
From: Kevin W Eliceiri <[hidden email]>
Date: Thursday, November 8, 2007 4:17 am
Subject: Re: First commercial single point confocal
To: [hidden email]

> Search the CONFOCAL archive at
> http://listserv.acsu.buffalo.edu/cgi-bin/wa?S1=confocal
>
> In 2003 Brad Amos and John White wrote a review for the Journal of
> Biology of the Cell entitled "How the Confocal Laser Scanning
> Microscope. entered Biological Research" that covers the history of
> the MRC500 development and timeline of other confocal developments.
> This is freely available at:
>
> www.biolcell.org/boc/095/0335/boc0950335.pdf
>
> In this review they state that one of the first public showings of
> their prototype was at
> the Symposium of the International Society for Analytical Cytology
> in Cambridge, UK, in 1987.
>
>
> Kevin W. Eliceiri
> Director
> Laboratory for Optical and Computational Instrumentation
> http://www.loci.wisc.edu
> Room 271 Animal Sciences
> 1675 Observatory Drive
> Madison, WI 53706
> Phone: [phone]
> Fax: [phone]
>
> ----- Original Message -----
> From: Patrick Van Oostveldt <[hidden email]>
> Date: Wednesday, November 7, 2007 11:50 am
> Subject: Re: First commercial single point confocal
> To: [hidden email]
>
> > Search the CONFOCAL archive at
> > http://listserv.acsu.buffalo.edu/cgi-bin/wa?S1=confocal
> >
> > Dear,
> >
> > As far as my memory is correct we recieved the first commercial
> MRC500
> > 
> > confocal in Europe. Feb 1988. At that time some prototypes of
> Leica 
> > were also displayed in EMBL. The EMBL system even had no
> possibility 
> >
> > to use conventional object observation and hence you needed a
> rather 
> >
> > blind imaging. Quite difficult if you have to look and search
> your 
> > object with alone confocal illumination and slowscanning.
> > Andrew Dixon, was than the most important person at BIORAD,
> probably 
> >
> > he has some  exact dates.
> >
> > As they told me the MRC500 was presented to the public in dec
> 1987 at 
> >
> > the american cell biology meeting.
> > Am I correct?
> >
> > Patrick
> >
> > Quoting "Wiegraebe, Winfried" <[hidden email]>:
> >
> > > Search the CONFOCAL archive at
> > > http://listserv.acsu.buffalo.edu/cgi-bin/wa?S1=confocal
> > >
> > > How do the Zeiss laser scanning and confocal microscopes fit
> into this
> > > history?
> > > According to their web-page they had 1982 the first commercial
> laser> > scanning microscope (not confocal), the LSM 44 and 1988 a
> confocal> > system (the LSM 10).
> > > Winfried
> > >
> > > ----------------------------------------------------------------
> --------
> > > --
> > > Winfried Wiegraebe, Ph.D.
> > > Dir. of Advanced Instrumentation & Physics
> > > Stowers Institute for Medical Research
> > > 1000 E. 50th St, Rm 454b
> > > Kansas City, MO 64110
> > > USA
> > >
> > > Phone: [phone]
> > > Cell:     [phone]
> > > Fax:     [phone]
> > > Email:  [hidden email]
> > > Web:    www.stowers-institute.org
> > > http://research.stowers-institute.org/wiw/
> > >
> > >
> > >
> >
> >
> >
> > --
> > Dep. Moleculaire Biotechnologie
> > Coupure links 653
> > B 9000 GENT
> >
> > tel [phone]
> > fax [phone]
>