Confocal Microscopist Position Description
The
Center for Ecogenomics in the Biodesign Institute at Arizona State
University has an
immediate opening for a scientist with extensive expertise in biological
confocal scanning light microscopy. We conduct life-sciences based
research into cellular physiology and disease on both mammalian cells (mainly
cancer) and microbes (deep ocean and human microbiome).
The
successful candidate will work in a multidisciplinary team environment serving
as the point person for research involving two state of the art imaging systems
(and several additional transmitted and fluorescence microscopes): 1) A
Nikon multi-mode confocal microscope system consisting of a LiveScan SFC (swept
field confocal), Spectral C1si (high-spectral resolution) confocal, and Perfect
Focus TE2000E2 inverted microscope with TIRF accessories; and 2) A novel cell
CT scanner for direct 3D absorption and fluorescence imaging of single cells.
We
seek a candidate with a PhD in cell or molecular biology or related field, and
a minimum of five years of recent, hands-on experience in all aspects of
biological fluorescence confocal laser scanning (and preferably
immunoperoxidase methods for absorption) microscopy: cell culture; probe
selection or design; cell labeling including immunocytochemical labeling and
fluorescence in situ hybridization; and image acquisition. Extensive
expertise in molecular biology and cell labeling is essential. Track
record of high-quality publications and extramural funding strongly preferred.
At
the core of the skill set we seek is the high level of expertise in fluorescent
probe selection and labeling technologies and protocols—and associated
probe excitation and emission considerations—necessary to provide optimal
signal to noise ratios and to achieve novel and ambitious scientific
objectives. This is a hands-on position requiring daily involvement in specimen
preparation and image data acquisition in addition to a thorough understanding
of the experimental goals and design.
The
successful candidate will assume full responsibility for managing and
optimizing the Center’s imaging facility, providing training and expert
input to users and active involvement in planning, design and execution of
complex research studies. Proficiency in slide- and tube-based cell
preparation and staining protocols and in 3D confocal imaging and image
rendering is highly desirable. Expertise in image processing and
analysis; mathematics and practical aspects of image reconstruction from
projections; other microscopies (various LM modes; TEM; scanned probe; x-ray);
molecular biological methods (PCR, FACS, laser capture microdissection);
histological techniques; cancer biopsy processing; statistics and design of
experiments is preferred but not required.
Application Deadline: September 18, 2009, then every two weeks until filled.
Application Procedure: Send cover letter, CV and the
names, email addresses and telephone numbers of three professional references
to [hidden email].
Continuation of this position is contingent on
satisfactory performance, availability of funding and the needs of the
program. A background check is required prior to an offer of
employment. AA/EOE
Roger H. Johnson, PhD, Research Laboratory Manager
Center for Ecogenomics, MC 6501
Biodesign Institute, Arizona State
University
Tempe, AZ 85287-6501
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