Permanent Senior Microscopist Position in Southampton, UK

[Raimund Ober]

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Dear Colleagues,

Please see the position announcement below.

Best regards,
Raimund Ober

 

Senior Microscopist: Head of Microscopy Group

University of Southampton; Cancer Sciences

Salary:   £38,460 to £48,677 Per annum
Full Time Permanent

Application instructions: https://jobs.soton.ac.uk/Vacancy.aspx?id=22856
<https://jobs.soton.ac.uk/Vacancy.aspx?id=22856&forced=2> &forced=2

Closing Date:  Sunday 01 March 2020

Applications are invited for the above position in the laboratory of
Professors Ober and Ward who are relocating their research group from the
USA. Their interdisciplinary research program is dedicated to the
development of advanced microscopy approaches, in particular single molecule
methods and subcellular trafficking studies. These approaches are being
applied to the development of novel antibody-based therapeutics that, to
date, have led to several new therapeutics that are currently in advanced
clinical trials. Their research is supported by major grants from the
Wellcome Trust, Cancer Research UK and collaborating biopharma companies.

Over recent decades the research group has pioneered several new microscopy
approaches, in particular single-molecule technologies, such as multi-focal
plane microscopy for the study of three dimensional subcellular dynamics of
proteins. The new microscopy laboratory will consist of several microscope
systems in custom-built space. The envisaged techniques include single
molecule microscopy, primarily three-dimensional approaches, using
multi-focal plane microscopy.

A key responsibility is the continued development of advanced microscopy
techniques, including multifocal plane microscopy, remote focusing
approaches for single molecule microscopy etc. You will also develop and use
multiphoton and confocal techniques, including fluorescence lifetime
approaches, in addition to more routine methods such as multi-color
live-cell microscopy in combination with TIRF illumination. The microscopes
will include commercial systems and systems built in-house. You will help to
build a cutting edge microscopy laboratory containing self-built and
commercial systems. The microscopy group will include several post-doctoral
fellows and Ph.D. students, who will also be engaged in methods development
and advanced experimentation.

A further responsibility will be the oversight and maintenance of the
microscopy equipment in the group.  You will be an efficient/capable manager
able to carry out your own research projects and oversee laboratory members
in a highly interdisciplinary setting. The position requires significant,
independent interactions with collaborators within and outside the
university.

You will have a major impact on the scientific mission of the laboratory by
carrying out and supervising advanced microscopy research projects related
to the use of existing methods and instrumentation development. You will be
involved in applying state-of-the-art technologies to cutting edge
biological projects, including the setup and maintenance of the microscopes
for use by the research group/collaborators.

The post is located in the Centre for Cancer Immunology at the Southampton
General Hospital, a newly constructed research building that is the result
of a significant fund-raising campaign. The Centre builds on a 40 year
history of pioneering immunology and cancer research at Southampton. It is
the first dedicated cancer immunology centre in the UK that brings the
complete research pipeline under one roof: from pioneering discovery science
to applied research and preclinical modelling and crucially onto
first-in-human clinical trials and beyond.  It is home to world-class
research facilities, state-of-the-art scientific laboratories and a Clinical
Trials Unit. This position is one of at least 20 new research and other
staff who will work with existing investigators to build on the exciting
progress already made in the field of cancer immunology.

While direct experience of the role described in the job description is not
a prerequisite, scientific experience in microscopy and optics at Ph.D.
level is required. Expertise in single molecule microscopy and cellular
microscopy is desirable. You will possess relevant academic
qualifications/work experience, good IT skills, ability to plan/organise
your workload, use your initiative, work well under pressure and communicate
effectively/professionally with a range of stakeholders within and outside
the organisation. This will be an ideal position for example, for an
applicant, with extensive experience in optics at the post-doctoral level,
wishing to continue their excitement for research in combination with the
managerial components of this position.

Informal enquiries should be directed to Professor Raimund J. Ober,
<mailto:[hidden email]> [hidden email].