The Dan L. Duncan Cancer Center at Baylor College of Medicine, located in the Texas Medical Center (Houston, TX), is seeking to fill a position of technical director of the Integrated Microscopy Shared Resource. This state-of-the-art imaging facility supports leading-edge, image-based studies for a broad range of investigators, performing mechanistic and screening studies in a variety of cancer biology-associated fields, including gene regulation, cell signaling, cell division/proliferation, stem cell biology, and virology.
The shared facility is equipped with confocal (Zeiss LSM 510, Nikon A1), deconvolution (Applied Precision), standard upright and inverted fluorescent scopes (Zeiss, Nikon), and a suite of robotic instrumentation for high throughput microscopy. Highly sophisticated image analysis tools are available for automated multiplex analyses with Pipeline Pilot (
www.accelrys.com), and CyteSeer (
www.valasciences.com). Robust statistical, modeling, reporting and pathway analysis tools support assay development for image-based screening using focused RNAi or compound libraries in conjunction with both the John S. Dunn Gulf Coast Consortium for Chemical Genomics, and the new BCM RNAi Core.
The technical director will report to the senior faculty director, and will be responsible for the day-to-day operation of the facility including:
* Supervising technical staff
* Maintaining equipment
* Billing shared resource users
* Scheduling instruments
* Training users on different instruments and software
* Providing assay development and technical advice to users for manual or high throughput imaging-based projects.
Participation in equipment and assay development grants will be expected. A well-qualified candidate could be appointed at the junior faculty level (instructor, non-tenure track), in the Department of Molecular and Cellular Biology.
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