*****
To join, leave or search the confocal microscopy listserv, go to:
http://lists.umn.edu/cgi-bin/wa?A0=confocalmicroscopyPost images on
http://www.imgur.com and include the link in your posting.
*****
Post Doctoral Fellow Position, McGill University, Montreal
Metastatic breast cancer, which is capable of spreading to distant organs and tissues,
represents the most deadly aspect of disease progression. Enhanced cell migration and invasion are
fundamental aspects of the metastatic phenotype. Our previous work has identified Lipoma Preferred Partner
(LPP) as an indispensable regulator of cell migration in breast cancer cells by virtue of its ability to control
focal adhesion turnover. LPP is normally restricted to mesenchymal cells, but we show that it is co-opted by
breast cancer cells that have undergone an epithelial-to-mesenchymal transition to increase their migratory
properties. Moreover, LPP is required for efficient breast cancer lung metastasis. Using innovative and
sophisticated live cell imaging approaches, we will elucidate the molecular mechanisms that allow LPP to
promote focal adhesion (FA) turnover. We will further elucidate the biological significance of LPP-mediated
actin remodeling on the development of breast cancer metastases. Combined, these multi-disciplinary
approaches will provide the first molecular insight and biological significance into how LPP-mediated
focal adhesion turnover increases breast cancer aggressiveness.
If interested send a cover letter and CV to
[hidden email]
Sincerely,
Claire
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Montreal Light Microscopy Course - Fundamentals, March 2-6, 2015, McGill University
Space is Limited Register now! Deadline February 20, 2015 -
http://www.curlydog.ca/mlmc2015Association of Biomolecular Resource Facilities (ABRF) Annual Meeting
March 28-31, 2015, St. Louis, MO, conf.abrf.org
Canadian Cytometry and Microscopy (CCMA) Symposium - Technologies to Treatments
June 18-20, 2015, Toronto, ON, www.cytometry.ca<
http://www.cytometry.ca/>
Need Microscope Access? Fill in our training request form:
http://www.mcgill.ca/lifesciencescomplex/core/imaging/newuserClaire M. Brown, PhD - McGill University - Assistant Professor, Physiology
Life Sciences Complex Advanced BioImaging Facility Director
3649 Promenade Sir William Osler - Bellini Building - Rm 137A - Montreal - Quebec - H3G 0B1
514-398-4400 ext 00795 (Phone) - 514-677-7493 (Cell) - 514-398-7452 (FAX)
[hidden email]<mailto:
[hidden email]> -
http://www.mcgill.ca/abif
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