Post-Doctoral Opening in AO Microscopy at UC Santa Cruz

[Joel Kubby]

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Dear Microscopist's,

We have an opening in our group at UC Santa Cruz for a post-doctoral
researcher in the area of microscopy using adaptive optics, as described
below. Feel free to contact me if you have any questions or suggestions for
applicants.

Best regards,

Joel Kubby

Chair, Electrical Engineering
UC Santa Cruz

<http://www.ucsc.edu/>UNIVERSITY OF CALIFORNIA, SANTA CRUZ

Department of Electrical Engineering

Post-Doctoral Researcher, Adaptive Optical Microscopy

The School of Engineering at the University of California, Santa Cruz
(UCSC) invites applications for the position of Post-Doctoral Researcer in
Adaptive Optical Microscopy, under the direction of Prof. Joel Kubby,
working in the Keck Center for Adaptive Optical Microscopy (
http://cfaom.soe.ucsc.edu/).  Applicants will participate in research
and should
be able to contribute to the application of adaptive optics in
state-of-the-art biological imaging. Possible related areas of research
might include neurobiology and developmental biology. The successful
candidate will be expected to align and operate new optical imaging and
optomechatronic systems.  We have a preference for candidates with
expertise in the use of various forms of biological microscopy (wide-field,
confocal, two-photon, structured illumination), deep-tissue imaging,
high-resolution imaging, and the correction and compensation of aberrations
in imaging systems including wavefront measurement using a Shack-Hartmann
wavefront sensor and correction using a deformable mirror.

*RANK:* Post-Doctoral Researcher

*SALARY:* *Commensurate with qualifications and experience*.

*BASIC QUALIFICATIONS:* A Ph.D in Biology, or a related discipline. Experience
in the application of advanced *in-vivo* biological light microscopy for
neurobiology and/or developmental biology. A demonstrated record of
publications in peer-reviewed journals.

*PREFERRED QUALIFICATIONS:*

• Familiarity with the application of adaptive optics for biological imaging
including wavefront sensing and correction.

• Experience in the preparation of biological specimens for optical imaging
including methods of tissue clearing.

• Demonstrate the ability to use wide-field, confocal and two-photon
microscopy.

• Ability to assemble and align prototype optical systems.

• Experience working with live fly, worm, fish and mouse models.

• Managing mouse colonies containing transgenic and inducible reporter mice.

• Working with viruses, DNA electroporation, and other fluorescent labeling
techniques.

• Working with Institutional Animal Care and Use Committee (IACUC) to
develop new procedures and protocols.

• A demonstrated record of publications in top-tier peer-reviewed journals.

*POSITION AVAILABLE:* January 1st, 2016.

*TERM OF APPOINTMENT:*  The initial appointment is for one year, with the
possibility of extension. Should the hiring unit propose reappointment, a
review to assess performance will be conducted.  Reappointment is also
contingent upon availability of funding.

*TO APPLY:*  Applications should be sent electronically to Prof. Joel Kubby
at the address below, and must include a letter of application that
addresses how you meet the basic and preferred qualifications, curriculum
vitae, at least eight selected publications (URLs or PDF format) and three
letters of reference*.  Documents/materials must be submitted as PDF files.

Send applications to: [hidden email]

*All letters will be treated as confidential per University of California
policy and California state law. For any reference letter provided via a
third party (i.e., dossier service, career center), direct the author to
UCSC’s confidentiality statement at http://apo.ucsc.edu/confstm.htm.

*CLOSING DATE:* To ensure full consideration, applications should be
complete and letters of recommendation received by December 15th, 2015.
The position will remain open until filled, but not later than December 31st,
2016.

[Charras, Guillaume]

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To join, leave or search the confocal microscopy listserv, go to:
http://lists.umn.edu/cgi-bin/wa?A0=confocalmicroscopy
Post images on http://www.imgur.com and include the link in your posting.
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Dear Microscopists,

We have an opening in our group at University College London for a post-doctoral
researcher in the area of Cell Biology and Biophysics. A description of the position follows.

Feel free to contact me if you have any questions.

Best,
Guillaume

___________________________________________________
Post-Doctoral Researcher, Cell Biology/ Biophysics

We are pleased to announce a call for applications for a postdoctoral researcher in the laboratory of Dr Guillaume Charras. This project seeks to understand what subcellular structures participate in the mechanics of cell monolayers, how these tissues sense and adapt to changes in their mechanical environment, and what mechanical forces underlie the individual cell behaviours leading to tissue morphogenesis and homeostasis.

Epithelial monolayers are amongst the simplest tissues in the body, yet they play fundamental roles in adult tissues, where they act as physical and mechanical barriers to separate the internal environment from the external environment, and in development, when the intrinsic forces they generate drive morphogenesis. At the molecular level, the mechanics of these simple tissues is believed to be dictated by the cytoskeletal and adhesive proteins that form the intercellular junctions that interface the constituent cells. However, a true quantitative understanding of how subcellular structures and individual cell behaviors govern tissue-scale monolayer mechanics is lacking. During development, tissue morphogenesis arises from the combination of a variety of individual cell behaviors such as oriented cell division, apical contraction, and cell intercalation. However, little is known about what mechanical forces and molecular processes act during each of these unitary cell behaviors. Mechanical forces appear to play a role in coordinating individual cell behaviors through mechanosensory feedback processes, yet our current understanding of mechanosensitivity remains qualitative.
The research will rely on a novel mechanical testing system recently developed in the Charras lab and interdisciplinary approaches to bridge the gap between molecular, cellular, and tissue-scales. This work will be carried out in collaboration with the laboratories of Dr Alexandre Kabla, Cambridge and Prof Buzz Baum, UCL. Work will be carried out at the London Centre for Nanotechnology. This ERC-funded project builds on previous work by the team (Harris AR et al, PNAS, 2012; Harris AR et al, J Cell Sci, 2014; Wyatt TPJ et al, PNAS, 2015).

The successful post-doc candidate will be an exceptional, highly-motivated and independent scientist with a PhD degree and a strong research track record in a relevant area of the Life Sciences or Physics, as well as experience at working within an interdisciplinary team. Experience of molecular cell biology, biophysics, microscopy, and programming is desired. Additional experience in developmental biology, and optogenetics will be an advantage. The position will be for three years starting on the 1st of March 2016. Appointment will be made with a salary in the range of £33,353-40,313 per year inclusive of London allowance and dependent on experience. Interested applicants should fill in an application online (see below) or email a cover letter, application form, CV and the names of two referees to Denise Ottley ([hidden email]). Informal inquiries about the position and project should be directed to Dr Guillaume Charras ([hidden email]) who will be supervising the research.

The official posting, Job description and Person Specification can be found at:
https://www.london-nano.com/our-people/vacancies/all. The reference number for this post is 1457077. Application forms can be downloaded from: http://www.ucl.ac.uk/hr/docs/download_forms/job_app.doc.
UCL is Taking Action for Equality.

**The closing date for applications is 17th of December 2015.**