Postdoc and PhD positions in single molecule microscopy

[Sripad Ram]

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I am posting this ad on behalf of my mentor. Please contact Raimund Ober
([hidden email]) for further enquires.

 

 

Post-doc and Ph.D. positions are available to work on the development of
methodology for fluorescence

microscopy related projects. The projects aim to develop novel imaging
modalities, image processing and data

analysis methods for superresolution single molecule approaches. Different
projects are available and they

include continued development of multifocal plane microscopy,
superresolution approaches, QD tracking,

point spread function modeling.

 

The positions will provide the opportunity to not only work on projects of
significant technical interest but

also to become familiar with the fundamental biological questions that are
being addressed in the laboratory.

Specifically the laboratory investigates the trafficking of antibodies in
live cell environment. A main emphasis

of the research is the investigation of the effects of the engineering of
the antibody binding to Fc receptors on

the cellular trafficking behavior and in vivo properties. These studies have
direct relevance to the rapidly

expanding use of antibodies in the biopharma industry as therapeutics in
autoimmunity, infectious diseases

and cancer. Funding is provided by the NIH and biopharma companies.

 

For more information on the research carried out in the laboratory see
www4.utsouthwestern.edu/wardlab, or

publications such as Optics Express, 17, 6881-6898, 2009; Biophys J., 95,
6025-6043, 2008; Proc. Natl. Acad.

Sci. USA, 104, 5889-5894, 2007; Proc. Natl. Acad. Sci. USA, 103, 4457-4462,
2006; Nature Biotechnol., 23,

1283-1288, 2005; Proc. Natl. Acad. Sci. USA, 101, 11076-11081, 2004; IEEE
Transactions Nanobioscience,

3, 237-242, 2004; J. Immunol., 172, 2021-2029, 2004; Biophys. J., 86,
1185-1200, 2004.

 

Highly motivated individuals with a background in any biological area,
(bio)engineering, biotechnology, chemistry, physics,

mathematics or any other physical science will be considered. Direct
experience is not

necessary. These positions provide the opportunity for the successful
candidate to gain experience in

advanced microscopic techniques applied to important problems in
biotechnology.

 

Please send inquiries (resume, names of referees etc.) to

Prof. Raimund J. Ober

University of Texas at Dallas

email: [hidden email]

 

 

 

[Teng-Leong Chew]

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Dear Colleagues,

This is not imaging related, but it is a very grave news that will affect
many of us. I urge you to read on.

On Dec. 7, 2010, the Scientific Management Review Board (SMRB)
recommended that the National Institutes of Health (NIH) realign its
resources to establish a new Center devoted to advancing translational
sciences. The action came in response to NIH Director Francis Collins’s
charge to the SMRB to formulate and recommend a plan for achieving
optimal organization for therapeutic development within NIH.

Due to the 2006 NIH Reauthorization Act, which capped the number
of institute/Centers at the current number (27), the NIH cannot create a
new center without eliminating an existing institute/center. As a result,
the NIH has decided to dissolve the NCRR and reassign its programs
and portfolios to other institutes/centers.

For more information:
http://feedback.nih.gov/index.php/ncats/intro-read-more/

Also, click on "up-to-date information" link on the page above.

It is a safe assumption that many American colleagues on this list have
benefitted immensely from the resources and programs of the NCRR,
especially the Shared Instrumentation Grants and monies that support
many comparative medicine centers.

This decision will greatly impact the abilities of core facilities to apply for
instrument grants. If the NCRR portfolio is to be divided and administered
by various individual institutes/centers, then our ability to bring together
investigators from different fields but with the same need (e.g., a confocal
or a flow cytometer) to apply for instrument grant will be immediately
crippled. This new initiative will also allow individual departments to
compete more successfully than facilities to obtain instruments due to
their tightly aligned scientific themes. This will become very wasteful for
the NIH very quickly as departments start duplicating instrumentation
(and the necessary technical staff) to run services currently shared by
many investigators supported by various NIH funds. The NCRR is a
uniquely important source of scientific infrastructure whose investments
have always been in the spirit of sharing. The ensuing dissolution will
eliminate that advantage in one stroke.

Several professional societies and federation of scientific societies have
voiced their concerns to the NIH leadership. Their letters can be found
here (some long URLs may break in half, please copy the whole link
to your browser)

smrb.od.nih.gov/dec7/pc/PublicComment14SMRB_NARRC_Let_Final.pdf

www.abrf.org/other/Announcements/ABRF_TMAT_Letter.pdf

www.faseb.org/Portals/0/PDFs/News_Room_PDFs/12.6.10 FASEB TMAT Letter.pdf

I urge you to voice your concerns through the following comment site:
http://feedback.nih.gov/index.php/ncats/ncats-comments/

Please urge the professional societies of which you are a member to
join the effort in voicing the concern against this initiative. I believe the
scientific community has been given neither sufficient time nor information
to consider and react to this swift decision.



Teng-Leong Chew, Ph.D.
Director, Cell Imaging Facility & Nikon Imaging Center
Director for University Imaging Resources
Northwestern University Feinberg School of Medicine
Chicago, IL 60611

[Linda Steer]

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FYI, I don't if you are still on the confocal list or aware of this.

Linda

On 1/1/2011 4:15 AM, Teng-Leong Chew wrote:

> *****
> To join, leave or search the confocal microscopy listserv, go to:
> http://lists.umn.edu/cgi-bin/wa?A0=confocalmicroscopy
> *****
>
> Dear Colleagues,
>
> This is not imaging related, but it is a very grave news that will affect
> many of us. I urge you to read on.
>
> On Dec. 7, 2010, the Scientific Management Review Board (SMRB)
> recommended that the National Institutes of Health (NIH) realign its
> resources to establish a new Center devoted to advancing translational
> sciences. The action came in response to NIH Director Francis Collins’s
> charge to the SMRB to formulate and recommend a plan for achieving
> optimal organization for therapeutic development within NIH.
>
> Due to the 2006 NIH Reauthorization Act, which capped the number
> of institute/Centers at the current number (27), the NIH cannot create a
> new center without eliminating an existing institute/center. As a result,
> the NIH has decided to dissolve the NCRR and reassign its programs
> and portfolios to other institutes/centers.
>
> For more information:
> http://feedback.nih.gov/index.php/ncats/intro-read-more/
>
> Also, click on "up-to-date information" link on the page above.
>
> It is a safe assumption that many American colleagues on this list have
> benefitted immensely from the resources and programs of the NCRR,
> especially the Shared Instrumentation Grants and monies that support
> many comparative medicine centers.
>
> This decision will greatly impact the abilities of core facilities to apply for
> instrument grants. If the NCRR portfolio is to be divided and administered
> by various individual institutes/centers, then our ability to bring together
> investigators from different fields but with the same need (e.g., a confocal
> or a flow cytometer) to apply for instrument grant will be immediately
> crippled. This new initiative will also allow individual departments to
> compete more successfully than facilities to obtain instruments due to
> their tightly aligned scientific themes. This will become very wasteful for
> the NIH very quickly as departments start duplicating instrumentation
> (and the necessary technical staff) to run services currently shared by
> many investigators supported by various NIH funds. The NCRR is a
> uniquely important source of scientific infrastructure whose investments
> have always been in the spirit of sharing. The ensuing dissolution will
> eliminate that advantage in one stroke.
>
> Several professional societies and federation of scientific societies have
> voiced their concerns to the NIH leadership. Their letters can be found
> here (some long URLs may break in half, please copy the whole link
> to your browser)
>
> smrb.od.nih.gov/dec7/pc/PublicComment14SMRB_NARRC_Let_Final.pdf
>
> www.abrf.org/other/Announcements/ABRF_TMAT_Letter.pdf
>
> www.faseb.org/Portals/0/PDFs/News_Room_PDFs/12.6.10 FASEB TMAT Letter.pdf
>
> I urge you to voice your concerns through the following comment site:
> http://feedback.nih.gov/index.php/ncats/ncats-comments/
>
> Please urge the professional societies of which you are a member to
> join the effort in voicing the concern against this initiative. I believe the
> scientific community has been given neither sufficient time nor information
> to consider and react to this swift decision.
>
>
>
> Teng-Leong Chew, Ph.D.
> Director, Cell Imaging Facility&  Nikon Imaging Center
> Director for University Imaging Resources
> Northwestern University Feinberg School of Medicine
> Chicago, IL 60611
>

[James Denegre]

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http://lists.umn.edu/cgi-bin/wa?A0=confocalmicroscopy
*****

Val,

Don't  know if you have already heard about this,

Jim


James Denegre, Ph.D.
Senior Manager
Imaging Sciences
The Jackson Laboratory
Bar Harbor, ME 04609
207.288.6648




On 1/1/11 4:15 AM, "Teng-Leong Chew" <[hidden email]> wrote:

*****
To join, leave or search the confocal microscopy listserv, go to:
http://lists.umn.edu/cgi-bin/wa?A0=confocalmicroscopy
*****

Dear Colleagues,

This is not imaging related, but it is a very grave news that will affect
many of us. I urge you to read on.

On Dec. 7, 2010, the Scientific Management Review Board (SMRB)
recommended that the National Institutes of Health (NIH) realign its
resources to establish a new Center devoted to advancing translational
sciences. The action came in response to NIH Director Francis Collins's
charge to the SMRB to formulate and recommend a plan for achieving
optimal organization for therapeutic development within NIH.

Due to the 2006 NIH Reauthorization Act, which capped the number
of institute/Centers at the current number (27), the NIH cannot create a
new center without eliminating an existing institute/center. As a result,
the NIH has decided to dissolve the NCRR and reassign its programs
and portfolios to other institutes/centers.

For more information:
http://feedback.nih.gov/index.php/ncats/intro-read-more/

Also, click on "up-to-date information" link on the page above.

It is a safe assumption that many American colleagues on this list have
benefitted immensely from the resources and programs of the NCRR,
especially the Shared Instrumentation Grants and monies that support
many comparative medicine centers.

This decision will greatly impact the abilities of core facilities to apply for
instrument grants. If the NCRR portfolio is to be divided and administered
by various individual institutes/centers, then our ability to bring together
investigators from different fields but with the same need (e.g., a confocal
or a flow cytometer) to apply for instrument grant will be immediately
crippled. This new initiative will also allow individual departments to
compete more successfully than facilities to obtain instruments due to
their tightly aligned scientific themes. This will become very wasteful for
the NIH very quickly as departments start duplicating instrumentation
(and the necessary technical staff) to run services currently shared by
many investigators supported by various NIH funds. The NCRR is a
uniquely important source of scientific infrastructure whose investments
have always been in the spirit of sharing. The ensuing dissolution will
eliminate that advantage in one stroke.

Several professional societies and federation of scientific societies have
voiced their concerns to the NIH leadership. Their letters can be found
here (some long URLs may break in half, please copy the whole link
to your browser)

smrb.od.nih.gov/dec7/pc/PublicComment14SMRB_NARRC_Let_Final.pdf

www.abrf.org/other/Announcements/ABRF_TMAT_Letter.pdf

www.faseb.org/Portals/0/PDFs/News_Room_PDFs/12.6.10 FASEB TMAT Letter.pdf

I urge you to voice your concerns through the following comment site:
http://feedback.nih.gov/index.php/ncats/ncats-comments/

Please urge the professional societies of which you are a member to
join the effort in voicing the concern against this initiative. I believe the
scientific community has been given neither sufficient time nor information
to consider and react to this swift decision.



Teng-Leong Chew, Ph.D.
Director, Cell Imaging Facility & Nikon Imaging Center
Director for University Imaging Resources
Northwestern University Feinberg School of Medicine
Chicago, IL 60611

[Patty Conrad]

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*****

This is a message I received from ASCB regarding the dissolution of the NCRR
and the SIG funding:

I have followed the discussions by the NIH Scientific Management Review
Board and a subsequent conference call by Dr. Collins that took place in early
December. Dr. Collins was clear that even if the programs currently housed at
the NCRR are reassigned, their operation will not be changed. The changes
being made to the NCRR do, however, appear to be a work in progress and
the Public Policy Committee and I will continue to follow it.

The ASCB Public Policy Committee discussed this at our meeting in December
at the ASCB Annual Meeting and we will continue to watch it.

Thank you for sharing your concern with me.

Please do not hesitate to stay in touch with me on this or any other issue.

Kevin

Kevin Wilson
ASCB Director of Public Policy

[Paul Herzmark]

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 ASCB = American Society of Cell Biologists
SIG = shared instrument grant
NIH = National Institutes of Health

But what is  NCRR?


Paul Herzmark


On Tue, Jan 4, 2011 at 10:52 AM, Patty Conrad <[hidden email]> wrote:

> *****
> To join, leave or search the confocal microscopy listserv, go to:
> http://lists.umn.edu/cgi-bin/wa?A0=confocalmicroscopy
> *****
>
> This is a message I received from ASCB regarding the dissolution of the
> NCRR
> and the SIG funding:
>
> I have followed the discussions by the NIH Scientific Management Review
> Board and a subsequent conference call by Dr. Collins that took place in
> early
> December. Dr. Collins was clear that even if the programs currently housed
> at
> the NCRR are reassigned, their operation will not be changed. The changes
> being made to the NCRR do, however, appear to be a work in progress and
> the Public Policy Committee and I will continue to follow it.
>
> The ASCB Public Policy Committee discussed this at our meeting in December
> at the ASCB Annual Meeting and we will continue to watch it.
>
> Thank you for sharing your concern with me.
>
> Please do not hesitate to stay in touch with me on this or any other issue.
>
> Kevin
>
> Kevin Wilson
> ASCB Director of Public Policy
>

[Patty Conrad]

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To join, leave or search the confocal microscopy listserv, go to:
http://lists.umn.edu/cgi-bin/wa?A0=confocalmicroscopy
*****

NCRR = National Center for Research Resources.
Read about it at http://www.ncrr.nih.gov/

The SIG is the shared instrumentation grant program whereby core facilities (or
others with at least 3 NIH grant recipient participants) can apply for $100K to
$600K to purchase high-end  equipment such as confocal, multiphotons,
phosphorimagers, high throughput, etc... any shared piece of equipment that
costs between this range.  See info at:
http://www.ncrr.nih.gov/biomedical_technology/shared_instrumentation/

deadline this year is March 23.

[Teng-Leong Chew]

*****
To join, leave or search the confocal microscopy listserv, go to:
http://lists.umn.edu/cgi-bin/wa?A0=confocalmicroscopy
*****

Thank you Patty for your update on the ASCB position.


Regards,
Leong


---
Teng-Leong Chew, Ph.D.
Director, Cell Imaging Facility & Nikon Imaging Center
Director for University Imaging Resources
Northwestern University Feinberg School of Medicine
Chicago, IL 60611
312-503-2841 (M, T, T)
847-491-7091 (W, F)