Postdoc and Researcher in Cell Biology/ Cellular Immunology / Imaging of intracellular traffic

[Oddmund Bakke]

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Department of Biosciences, University of Oslo
Researcher and Postdoctoral Research Fellow in Cell Biology/ Cellular
Immunology/Intracellular Imaging
http://uio.easycruit.com/vacancy/1359027/96323?iso=no
The postdoc position and the researcher position are available at the Department
of Biosciences, University of Oslo Norway and funded by the Norwegian Research
Council and the Norwegian Cancer Society. Project "The intracellular pathway for
MHC Class II antigen presentation". The researcher and the postdoc will work in
the group of prof. Oddmund Bakke at the Department of Biosciences, University of
Oslo and part time at NKI, the Dutch Cancer Institute in Amsterdam.  

The positions are for two years, but a one-year prolongation is possible. Within the
framework of the position duties may be assigned. In regards to the post doctoral
position, no one can be appointed for more than one fixed-term period at the same
institution.

Job Description
The project focuses primarily on unraveling the function of the endocytic pathway
toward antigen loading using biophysical techniques, molecular biological
techniques, biochemistry, imaging (e.g. live imaging) and
molecular/imaging/biochemical screens in cell culture systems and cells from
knock out/knock in mice. The project will focus on unraveling the pathway towards
MHC II antigen loading, in particular for the molecules that associate with the
transport to and from this compartment in immune cells, both in cell lines and in
human dendritic cells (See e.g. Neefjes et al., 2011, Nature immunology and
publications by the supervisors (Medline, in particular Oddmund Bakke and
Jacques Neefjes). We also work, together with a clinical group, and we have
patented a vaccine for immunotherapy by improving loading of the MHC molecules,
both MHC class I and class II. The Bakke group is a member of a CoE, Centre for
Immune Regulation and prof Oddmund Bakke is also the head of the National
imaging platform NorMIC Oslo, with a wide range of imaging equipment, including
equipment at the Oslo University hospital, a node headed by prof Harald Stenmark.

The work will include collaboration with national and international groups in
particular Prof. Jacques Neefjes at the Dutch Cancer Centre, NKI in Amsterdam and
with the Preben Morth Group who is a part of the Centre for Molecular Medicine
Norway, home page.

Qualifications
The Faculty of Mathematics and Natural Sciences has a strategic ambition of being
a leading research faculty. Candidates for these fellowships will be selected in
accordance with this, and expected to be in the upper segment of their class with
respect to academic credentials.

The candidates must have a PhD or other corresponding education equivalent to a
Norwegian doctoral degree in molecular biology, cell biology, biophysics or
biochemistry.

We are seeking highly motivated and skilled researchers with broad and extensive
experience within one or more of the following areas: advanced imaging, molecular
biology, cellular immunology, cell biology, biochemistry, and protein chemistry.
Prior experience with intracellular membrane/protein traffic and library screening
will be considered a strong advantage. One of the positions will preferentially need
extensive experience with advanced cellular imaging and membrane trafficking
whereas one will be more focused towards cell biology/intracellular
membrane/organelle biogenesis and transport and immunological techniques.

The main purpose of post-doctoral research fellowships is to qualify researchers for
work in top academic positions within their disciplines.                

Please also refer to the regulations pertaining to the conditions of employment for
post-doctoral fellowship positions.
A good command of English is required.
Salary:
Position code 1352 for post doctoral research fellow, Pay Grade: 57 – 65  (NOK
482 800 – 559 600 per year, depending on qualifications and seniority).

Position code 1109 for researcher, Pay Grade: 57 – 65  (NOK 482 800 – 559 600
per year, depending on qualifications and seniority).
The application must include:
Application letter, please indicate on your application letter which position you are
applying for.
CV (summarizing education, positions, pedagogical experience, administrative
experience and other qualifying activity)
Copies of educational certificates, transcript of records and letters of
recommendation
Documentation of English proficiency
A complete list of publications and all academic works that the applicant wishes to
be considered by the evaluation committee
Names and contact details of 2-3 references (name, relation to candidate, e-mail
and telephone number)
Please remember that all documents should be in English or a Scandinavian
language.

In accordance with the University of Oslo’s equal opportunities policy, we invite
applications from all interested individuals regardless of gender or ethnicity.

Region: Oslo
Working hours:
Full-time
Working days:
Day
Application deadline:
15 April, 2015
Reference number:
2015/3946
Home page: http://www.mn.uio.no/ibv/
Contacts:
Professor Oddmund Bakke
Telephone: [phone]
Mobile: [phone]
http://uio.easycruit.com/vacancy/1359027/96323?iso=no

[Charras, Guillaume]

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Dear all,

I have a vacancy for a post-doctoral researcher at University College London. The advertisement follows. The closing date is May 15th.

Best wishes,
Guillaume

__________________________________________________________________


Postdoctoral Researcher Position at University College London in the London Centre for Nanotechnology

We are pleased to announce a call for applications for a postdoctoral researcher to study the morphogenesis of epithelial cell monolayers in the laboratory of Dr Guillaume Charras.
Epithelial monolayers are amongst the simplest tissues in the body, yet they play fundamental roles in adult tissues, where they act as physical and mechanical barriers to separate the internal environment from the external environment, and in development, when the intrinsic forces they generate drive morphogenesis. During development, tissue morphogenesis arises from the combination of a variety of individual cell behaviours such as oriented cell division, apical contraction, and cell intercalation. Similar cellular-scale behaviours also underlie the adaptation of tissues to changes in their mechanical environment. However, little is known about what mechanical forces and molecular processes act during each of these unitary cell behaviours and how they are integrated at the tissue-scale.

The proposed research project aims at exploring tissue morphogenesis from the bottom-up using epithelial monolayers devoid of a substrate combined with optogenetic techniques to control cell behaviour and trigger tissue morphogenesis. The project will use live imaging, mechanical testing, and computational modelling. This work will be carried out in close collaboration with the laboratory of Dr Alexandre Kabla, Cambridge and Dr Buzz Baum, UCL. This ERC-funded project builds on previous work by members of the team (Harris AR et al, PNAS, 2012; Kuipers DK et al, J Cell Sci, 2014; Harris et al, J Cell Sci, 2014; Wyatt T et al, PNAS, 2015, accepted). Work will be carried out at the London Centre for Nanotechnology (www.london-nano.com).

The successful candidate will be an exceptional, highly-motivated and independent scientist with a PhD degree and a strong research track record in a relevant area of the life sciences, as well as experience at working within an interdisciplinary team. Experience of molecular cell biology, microscopy, and programming is desired. Additional experience in biophysics, developmental biology, and optogenetics will be an advantage. The position will be for three years starting on the 1st of September 2015. Appointment will be made with a salary in the range of £33,353-40,313 per year inclusive of London allowance and dependent on experience.

Interested applicants should fill in an application online (see below) or email a cover letter, application form, CV and the names of two referees to Denise Ottley ([hidden email]). Informal inquiries about the position and project should be directed to Dr Guillaume Charras ([hidden email]) who will be supervising the research.

The official posting, Job description and Person Specification can be found at:
https://www.london-nano.com/our-people/vacancies/all
The reference number for this post is 1457077.

Application forms can be downloaded from: http://www.ucl.ac.uk/hr/docs/download_forms/job_app.doc.

Further details can be seen at http://www.london-nano.ucl.ac.uk/content/lcncareers 

Taking Action for Equality

The closing date for applications is 15th of May 2015

[Charras, Guillaume]

*****
To join, leave or search the confocal microscopy listserv, go to:
http://lists.umn.edu/cgi-bin/wa?A0=confocalmicroscopy
Post images on http://www.imgur.com and include the link in your posting.
*****

Dear all,

I have a vacancy for a post-doctoral researcher at University College London, London, UK.

The advertisement follows. The closing date is May 15th.

Best wishes,
Guillaume

__________________________________________________________________


Postdoctoral Researcher Position at University College London in the London Centre for Nanotechnology

We are pleased to announce a call for applications for a postdoctoral researcher to study the morphogenesis of epithelial cell monolayers in the laboratory of Dr Guillaume Charras.

Epithelial monolayers are amongst the simplest tissues in the body, yet they play fundamental roles in adult tissues, where they act as physical and mechanical barriers to separate the internal environment from the external environment, and in development, when the intrinsic forces they generate drive morphogenesis. During development, tissue morphogenesis arises from the combination of a variety of individual cell behaviours such as oriented cell division, apical contraction, and cell intercalation. Similar cellular-scale behaviours also underlie the adaptation of tissues to changes in their mechanical environment. However, little is known about what mechanical forces and molecular processes act during each of these unitary cell behaviours and how they are integrated at the tissue-scale.

The proposed research project aims at exploring tissue morphogenesis from the bottom-up using epithelial monolayers devoid of a substrate combined with optogenetic techniques to control cell behaviour and trigger tissue morphogenesis. The project will use live imaging, mechanical testing, and computational modelling. This work will be carried out in close collaboration with the laboratory of Dr Alexandre Kabla, Cambridge and Dr Buzz Baum, UCL. This ERC-funded project builds on previous work by members of the team (Harris AR et al, PNAS, 2012; Kuipers DK et al, J Cell Sci, 2014; Harris et al, J Cell Sci, 2014; Wyatt T et al, PNAS, 2015, accepted). Work will be carried out at the London Centre for Nanotechnology (www.london-nano.com).

The successful candidate will be an exceptional, highly-motivated and independent scientist with a PhD degree and a strong research track record in a relevant area of the life sciences, as well as experience at working within an interdisciplinary team. Experience of molecular cell biology, microscopy, and programming is desired. Additional experience in biophysics, developmental biology, and optogenetics will be an advantage. The position will be for three years starting on the 1st of September 2015. Appointment will be made with a salary in the range of £33,353-40,313 per year inclusive of London allowance and dependent on experience.

Interested applicants should fill in an application online (see below) or email a cover letter, application form, CV and the names of two referees to Denise Ottley ([hidden email]). Informal inquiries about the position and project should be directed to Dr Guillaume Charras ([hidden email]) who will be supervising the research.

The official posting, Job description and Person Specification can be found at:
https://www.london-nano.com/our-people/vacancies/all
The reference number for this post is 1457077.

Application forms can be downloaded from: http://www.ucl.ac.uk/hr/docs/download_forms/job_app.doc.

Further details can be seen at http://www.london-nano.ucl.ac.uk/content/lcncareers

Taking Action for Equality

The closing date for applications is 15th of May 2015

[Bernd Mueller-Zuelow]

*****
To join, leave or search the confocal microscopy listserv, go to:
http://lists.umn.edu/cgi-bin/wa?A0=confocalmicroscopy
Post images on http://www.imgur.com and include the link in your posting.
*****



LaVision
BioTec announces the first International Users’ Meeting on their
UltraMicroscope, a platform for information exchange on light sheet microscopy.

 

The
first LaVision BioTec UltraMicroscope User Meeting will take place at the Max Planck Institute
for Molecular Biomedicine in Münster, 21-22 September. Participants are cordially invited
to join with all active and prospective UltraMicroscope users in a forum on the
latest developments in light sheet microscopy.

 

An
international group of speakers will provide the backbone for the meeting which
will comprise three scientific sessions.

 

Confirmed
speakers:

 

·        
Vance
Lemmon, University of Miami

·        
Ali
Ertürk, Ludwig Maximilian University, Munich

·        
Pablo
Ariel, Rockefeller University, New York

·        
Friedemann Kiefer, Max Planck Institute, Muenster

·        
Morgane
Belle, Institut de la Vision, Paris

·        
Julia
Bode, German Cancer Research Center Heidelberg

·        
Sylvaine
Guerit, Medical School Goethe University Frankfurt

·        
Jessica
Lerch, Department of Neuroscience, Ohio State University, Columbus

·        
Yougunn
Prakashkumar, University of Southampton

·        
Torben
Seested Johansen, Copenhagen

·        
Tan
Yingrou, Immunology Network, Singapore

 

 

Workshops:

 

·        
Ultramicroscope
I & II

·        
Image
acquisition software ImSpector

·        
Data
processing

·        
Clearing

 

Due to
limited space a confirmed registration is strictly required; please contact our
organizing team at [hidden email].



Best
regards

 

Bernd
Mueller-Zuelow

[hidden email]

LaVision
BioTec GmbH, Astastr. 14, 33617 Bielefeld, Germany

Tel: +49
521 915139-0, Fax: [phone] www.lavisionbiotec.com