Re: FRAP system (Commercial Response) Nitrogen Laser System Sales & Service - www.337nm.com

[R. Eric King]

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Dear List,

FYI-

We sell and service the LSI, Thermo Science, SRS, and Spectra-Physics models
of Nitrogen laser systems (VSL-337, VSL-377ND, VSL-337i, VSL-337ND-S,
VSL-337Si, & NL100) found within some of your facilities  MaldiTOF, FRAP,
Dye, etc.; instruments.

Also, here is the link to the Argon & Krypton Ion laser wavelength charts,
that did not survive when originally disseminated to the list:
http://www.laserinnovations.com/coherentlaser_innova-300_LaserInnovations.ht
m

Thank you for your time, and have a great weekend
Best Regards,
 
R. Eric King
OEM & International Sales Manager
[hidden email]
www.LaserInnovations.com
 
LASER
     INNOVATIONS
1150 East Main Street
Santa Paula, CA 93060
[phone]
[phone] fax
 
www.CoherentLaser.com
www.244nm.com <http://www.244nm.com/>
www.337nm.com
www.355nm.com <http://www.355nm.com/>
www.488nm.com
www.532nm.com <http://www.532nm.com/>
www.Solidimaging.com

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-----Original Message-----
From: Confocal Microscopy List [mailto:[hidden email]] On
Behalf Of Michael Mohammadi
Sent: Friday, August 24, 2012 6:20 AM
To: [hidden email]
Subject: Re: FRAP system

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[commercial response]

Hi Deepak,

We thank you for your interest in both the Andor Mosaic and the Andor
FRAPPA.  I'd be happy to differentiate these products for you and will leave
the competitive comparisons to the 3i product out of my response.

The Andor Mosaic system is built around a DMD- a small chip (similar to a
camera CCD) that has ~a million tiny mirrors (rather than pixels) that allow
the user to have complete control over the spatial/temporal aspects of their
illumination (ie FRAP laser, LED's for optogenetics, etc).  The advantage
here is that there is zero delta time in illuminating multiple ROI's of any
shape/size and since the mirrors function on 10's of uS time scale, pattern
switching is extremely fast.  The power density of Mosaic can be an issue
for some FRAP applications, but we have dozens of publications with Mosaic
that I can provide to you spanning a variety of applications.  If
speed/flexibility is your priority the Mosaic may be the best suited for
your application.

The Andor MicroPoint and Andor FRAPPA both utilize a galvonometer based
approach to guide a single spot of light around the field of view.  The
MicroPoint is unique in that it uses an extremely high power nitrogen pumped
laser (that uses individual dye cells which can be swapped in/out), is
diffraction limited in spot size, and comes in both manual and galvo based
versions (works great for FRAP, ablation, cutting nerves, industrial
applications, etc).   In comparison, the FRAPPA can mount to the epi port or
to a c-mount (for instance in line with a spinning disc) and it moves light
around the sample much faster than MicroPoint and will integrate lasers that
are also used for TIRF, or with the MPU on the Andor spinning disc system
(Revolution XD).  FRAPPA may be the way to go if speed/larger/multiple ROI's
are necessary (and when the power density of Mosaic is not sufficient for
your application) and is the easy choice over MicroPoint if you're working
with photoconvertible probes.

Each product listed is extremely flexible as to what make/model of
microscope it will work with as well as what software support exists.

I would be happy to take this discussion off the listserv to go into more
detail about any of the systems.  Each product is very unique and the right
option for you will depend on your sample prep, targeted fluorophores and
the detail of your existing microscope and application needs.  Please feel
free to contact me at your convenience.  [hidden email]

Cheers,

Michael

Andor Technology
Michael Mohammadi
Business Development Manager, AI/DSD, Americas
Cell Phone: [phone]
Support: [hidden email]

________________________________________
From: Confocal Microscopy List [[hidden email]] on behalf
of Deepak Saini [[hidden email]]
Sent: Wednesday, August 22, 2012 11:19
To: [hidden email]
Subject: FRAP system

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Does anyone have any comparative information on FRAP - photo activation
system
compatible with epifluorescence microscopes. I have been offerred the
following options

1. Mosaic module from Andor, previously photonic instruments
2. FRAP-PA from Andor
3. Vector from 3i.

Any input about these systems would be greatly appreciated.

Thanks,

D.


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