You might also look at the Dmetrix systems. I have limited
experience with them, but they were invented at the University of Arizona and
are a local company. They are used extensively to scan slides for our
Medical School’s histology class.
No commercial interest.
Doug
^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^
Douglas W. Cromey, M.S. - Assistant Scientific Investigator
Dept. of Cell Biology & Anatomy, University of Arizona
1501 N. Campbell Ave, Tucson, AZ 85724-5044 USA
office: AHSC
4212 email: [hidden email]
voice: 520-626-2824
fax: 520-626-2097
http://swehsc.pharmacy.arizona.edu/exppath/
Home of: "Microscopy and Imaging Resources on the WWW"
From: Confocal Microscopy
List [mailto:[hidden email]] On Behalf Of George
McNamara
Sent: Sunday, December 20, 2009 11:04 AM
To: [hidden email]
Subject: Re: Digital Slide Scanners
Hi Yevgeniy,
In addition to the scanners you mentioned, you should also check out
Bioimagene since their scanners are likely lowest price. Leica is also coming
out with a DSI (may not have fluorescence in first iteration). I am surprised
you did not mention Aprio - which is one of the leaders in this field and has a
fluorescence scanner (I consider Aprio's software prices to be high). Yokogawa
has introduced an impressively pricey confocal DSI. Genetix/Applied Imaging
bought SlidePath - an interesting combination of microscope based units
(CytoVision) and software. Genetix also offers one of the slide loading devices
for use on microscopes (SL-50, GSL-120, or similar names), that various imaging
software products support - so you could make a home built unit. I was unimpressed
with the images from the allen Brain Atlas project, but you might look to see
what they used for hardware.
Hamamatsu's new NanoZoomer II should be fast.
I don't know if BPI's TissueScope can be mated to a slide loader - you can
check them out at http://www.confocal.com/PRODUCTS/Tissuescope.html
One note about brightfield scanning - Bioimagene may be the only company that
has engineered their scanners to accept the slide carriers from
autostaining/coverslipping stations, for example from Sakura. The other
companies appear rather clueless about having fast scanners that require some
technician to manually move a whole lot of slides from coverslipper to trays to
others. If you are doing both brightfield and fluorescence now, consider having
different machines for each.
I encourage checking out the messages at the Digital Pathology group of
linkedin, http://www.linkedin.com/groups?gid=163106&trk=hb_side_g
best wishes,
George
At 12:39 PM 12/8/2009, you wrote:
Dear all
I have some
questions for those of you who has experience with digital slide
scanners. Our lab currently has a Mirax scanner from Zeiss and we are
also looking at the Pannoramic scanner from 3d Histech, as well as the
Nanozoomer from Olympus. We would like to purchase a second scanner in
addition to our Mirax, and if anybody can share their impressions about the
scanners they have, it would be very helpful and much appreciated.
The issues
that we are considering are obviously scan speed, especially with fluorescent
scanning. Also, how many fluorescent channels the machine is able to scan
at the same time. The reliability and the service quality of the scanner
is also very important. Another issue is the pricing. Please share
your impressions of the costs of different scanners, since the prices quoted
seem to vary from institution to institution. We are alsko looking at a
leasing schedule, and if anybody leases these kinds of scanners, any info on
the costs would also be greatly appreciated. Any other pros/cons that you
are willing to share will be helpful as well.
Thank you all
very much in advance,
Respectfully,
Yevgeniy
George McNamara, Ph.D.
Image Core Manager
Analytical Imaging Core Facility
University of Miami, Miller School of Medicine
Miami, FL 33136
[hidden email]
[hidden email]
305-243-8436 office
http://www.sylvester.org/AICF
(Analytical Imaging Core Facility)
http://www.sylvester.org/AICF/pubspectra.zip
(the entire 2000+ spectra .xlsx file is in the zip file)
http://home.earthlink.net/~geomcnamara
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