Re: Not a confocal question

Posted by Begley, James G on
URL: http://confocal-microscopy-list.275.s1.nabble.com/Not-a-confocal-question-tp592717p592718.html

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This is a very common problem with cells growing in culture.  Usually, coating the cover slips with a substrate like poly-D-lysine or collagen will take care of the problem, but there are some cell lines that will never grow as well on glass as plastic.

Jim Begley
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-----Original Message-----
From: Confocal Microscopy List [mailto:[hidden email]] On Behalf Of vaishali kailaje
Sent: Thursday, April 03, 2008 6:19 AM
To: [hidden email]
Subject: Not a confocal question

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http://listserv.acsu.buffalo.edu/cgi-bin/wa?S1=confocal

Dear All
We are working with B16F10 melanoma cell line  which
is a highly adhesive line , recently we are facing the
problem of growing them . When we grow them in petri
plates it spreads very well but when seeded on
coverslips it remains rounded. What could be the
possible reason.
Regards
Vaishali


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