Re: seeking suggestions on new sCMOS camera

Posted by Nico Stuurman-3 on
URL: http://confocal-microscopy-list.275.s1.nabble.com/seeking-suggestions-on-new-sCMOS-camera-tp7579501p7579509.html

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John Oreopoulos did a nice comparison of EMCCDs and sCMOS cameras on spinning disk: http://www.spectral.ca/_files/file.php?fileid=fileWFBaXTDIaW&filename=file_4_CSU_Camera_Comparison__sCMOSvsEMCCD.pdf

B.t.w., to do a fair comparison, you will need to change the magnification to the camera.  Hopefully, your current setup is optimized for the 16 micron pixels in your EMCCD.  Swapping in the sCMOS without changing magnification will give you a lot of empty magnification that will adversely affect noise characteristics.  Binning does not really help since in a CMOS all pixels are read out individually anyways (i.e. hardware and software binning does the same thing, unlike CCDs).

Best,

Nico