http://confocal-microscopy-list.275.s1.nabble.com/IMAGING-OF-CELLULOSE-tp7582017p7582035.html
uniformly, especially cotton cell walls. It overcomes the irritating
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>Cotton does contain small amounts of protein. It is unlikely that the
>cellulose would fluoresce.
>
>-----Original Message-----
>From: Confocal Microscopy List [mailto:
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>On Behalf Of Guy Cox
>Sent: Thursday, 8 May 2014 3:54 a.m.
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>Subject: Re: IMAGING OF CELLULOSE
>
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>I totally endorse TDE as an embedding medium but I am puzzled by acrolein
>inducing fluorescence in cellulose. Can someone explain the chemistry?
>I thought acroleon reacted with proteins.
>
> Guy
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>Sent: 08 May 2014 00:04
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>Subject: Re: IMAGING OF CELLULOSE
>
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>I have recently done some confocal imaging of cotton fibers. For deeper
>penetration, less scattering in single photon fluorescence imaging,
>rather than Calcofluor White I suggest staining with orange or
>red-fluorescing dyes - some have been already mentioned, like Congo Red.
>The fluorescent version of Periodic Acid-Schiff staining works great (use
>propidium iodide as pseudo-Schiff reagent; Truernit, E., H. Bauby, et al.
>(2008). "High- resolution whole-mount imaging of three-dimensional tissue
>organization and gene expression enables the study of Phloem development
>and structure in Arabidopsis." Plant Cell 20(6): 1494-1503).
>As an alternative to fluorescence staining, I have also used vapor
>fixation with acrolein, which tends to induce very strong
>autofluorescence, at least in cotton fibers. This is useful if you do
>not want to expose the fibers to water and induce swelling.
>For imaging with oil immersion objectives I used 2,2-thioidiethanol as a
>mounting medium with good success.
>Staudt, T., M. C. Lang, et al. (2007). "2,2'-thiodiethanol: a new water
>soluble mounting medium for high resolution optical microscopy."
>Microscopy Research and Technique 70(1): 1-9.
>
>Stan Vitha
>Microscopy and Imaging Center
>Texas A&M University
>
>
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