Re: General question: Software vs. hardware

Posted by Csúcs Gábor-3 on
URL: http://confocal-microscopy-list.275.s1.nabble.com/General-question-Software-vs-hardware-tp7589316p7589335.html

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Connected to the same thread I would like your opinion about the new Leica davalopment (they call it "computational clearing" and sell it under the name "Thunder".
They are very resistant to tell any mathematical details about it (even in a recently published white paper). Based on some rudimentaqry explanation it seems (really my subjective interpretation)that they do a wavelet conversion, filter out the large spatial components (claiming that those correspond to the out-of-focus background) and then transfer back the data. With this they claim to have the same effect as structured illumination (e.g. ApoTome) or a spinning disk (though this is a clear overstatement). Any thoughts from the community?

Greetings Gabor