looking for a recent review/book chapter

[doust mehraban]

Hi All,

I would appreciate it if you could guide me to a recent review or book chapter that you have found particularly useful on the use confocal microscopy (various techniques) in early drug development.

Thanks!

-Majid

Majid Ghoddusi, DVM, PhD

Experimental Pathology Group

Novartis Institutes for BioMedical Research

4560 Horton Street

Emeryville, California, 94608 USA

Office: [phone]   Fax: [phone]

[hidden email]

 

[B. Prabhakar Pandian]

Hello Everybody,
                               This may be an off topic question, but I
am hoping that somebody can point me in the right direction. I am
looking for a zebra fish cell line. Does anybody know of any vendor who
sells them.

Thanks,

-Prabhakar

--

[Gens, John Scott]

Prabhakar-

The go-to source online for all things zebrafish related is:

http://zfin.org/cgi-bin/webdriver?MIval=aa-ZDB_home.apg

Pretty sure that should get you started in a fruitful direction.

Cheers,

Scott




--
J. Scott Gens, Ph.D.
Biocomplexity Institute
Indiana University Physics
Office:     Room 047H, Simon Interdisciplinary Sciences Bldg.
Multi-photon Confocal: 063 Swain Hall West.
Bloomington IN 47405
812-855-7946
[hidden email]



Quoting "B. Prabhakar Pandian" <[hidden email]>:

> Hello Everybody,
>                               This may be an off topic question, but
> I am hoping that somebody can point me in the right direction. I am
> looking for a zebra fish cell line. Does anybody know of any vendor
> who sells them.
>
> Thanks,
>
> -Prabhakar
>
> --
>

[Dana Hill]

ATCC has several

On Mon, Jun 7, 2010 at 2:13 PM, B. Prabhakar Pandian <[hidden email]> wrote:

Hello Everybody,
                             This may be an off topic question, but I am hoping that somebody can point me in the right direction. I am looking for a zebra fish cell line. Does anybody know of any vendor who sells them.

Thanks,

-Prabhakar

--

[B. Prabhakar Pandian]

Thank you.

-Prabhakar

On 6/7/2010 4:28 PM, J. Scott Gens, PhD wrote:

> Prabhakar-
>
> The go-to source online for all things zebrafish related is:
>
> http://zfin.org/cgi-bin/webdriver?MIval=aa-ZDB_home.apg
>
> Pretty sure that should get you started in a fruitful direction.
>
> Cheers,
>
> Scott
>
>
>
>
> --
> J. Scott Gens, Ph.D.
> Biocomplexity Institute
> Indiana University Physics
> Office:     Room 047H, Simon Interdisciplinary Sciences Bldg.
> Multi-photon Confocal: 063 Swain Hall West.
> Bloomington IN 47405
> 812-855-7946
> [hidden email]
>
>
>
> Quoting "B. Prabhakar Pandian" <[hidden email]>:
>
>> Hello Everybody,
>>                               This may be an off topic question, but
>> I am hoping that somebody can point me in the right direction. I am
>> looking for a zebra fish cell line. Does anybody know of any vendor
>> who sells them.
>>
>> Thanks,
>>
>> -Prabhakar
>>
>> --
>>
>
>

--

---------------------------------------------------------


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[George McNamara]

P. Liu, S. Ahmed, T. Wohlland 2008 The F-techniques: advances in receptor protein studies. Trends Endocrinol Metab 19: 181-190. PMID: 18387308

Thomas N 2010

High-content screening: a decade of evolution.

J Biomol Screen 15:1-9.  (the author is with GE Healthcare - one of the vendors mentioned). I suggest searching JBS for other recent confocal articles.

Zanella F, Lorens JB, Link W 2010

High content screening: seeing is believing.

Trends Biotechnol 28(5):237-45.

Lang P, Yeow K, Nichols A, Scheer A 2006 Cellular imaging in drug discovery. Nat Rev Drug Discov 5: 343-56. Review.PMID: 16582878. more cells than confocal ... this is one hit by searching pubmed with:   confocal "drug discovery" review

Not discovery, but I thought these were interesting with respect to confocal & drugs:

Daly CJ, McGrath JC 2003 Fluorescent ligands, antibodies, and proteins for the study of receptors. Pharmacology & Therapeutics 100 :101–118. (if you like this, check out other papers from the authors, such as Arribas et al)

J Physiol 584.1 (2007) p5–9.
Arribas SM, Daly CJ, Gonzalez MC, McGrath JC 2007 Imaging the vascular wall using confocal microscopy


Enjoy,

George

At 04:08 PM 6/7/2010, you wrote:

Hi All,

I would appreciate it if you could guide me to a recent review or book chapter that you have found particularly useful on the use confocal microscopy (various techniques) in early drug development.

Thanks!

-Majid



Majid Ghoddusi, DVM, PhD
Experimental Pathology Group
Novartis Institutes for BioMedical Research
4560 Horton Street
Emeryville, California, 94608 USA
Office: [phone]   Fax: [phone]
[hidden email]
 

George McNamara, Ph.D.
Image Core Manager
Analytical Imaging Core Facility
University of Miami, Miller School of Medicine
Miami, FL 33136
[hidden email]
[hidden email]
305-243-8436 office
http://www.sylvester.org/AICF (Analytical Imaging Core Facility)
http://www.sylvester.org/AICF/pubspectra.zip (the entire 2000+ spectra .xlsx file is in the zip file)
http://home.earthlink.net/~geomcnamara

[B. Prabhakar Pandian]

Hello Everybody:
                            A couple of months ago there was a thread on
cleaning protocols for cover slips and microscope slides. I was emailing
to see if anyone can recommend
coverglass holders which can be used in these solutions. I am
specifically looking for the 35mmx60mm coverglass and 25mmX60mm holders
. Any pointers to vendors will be great.

Thanks,

-Prabhakar

[S. Pagakis (IIBEAA)]

A senior postdoc (“experienced researcher”) position for a microscopy & imaging expert is available at Biomedical Research Foundation, Academy of Athens (BRFAA) (http://www.bioacademy.gr/) as part of the FP7 Infrastructure grant “TRANSMED” (Translating basic research findings in major human diseases: emphasis on obesity, metabolic syndrome and neurodegeneration) (http://www.bioacademy.gr/transmed).

Candidates should have a PhD in Biology, Neurosciences, Bioengineering or related disciplines, and at least 3 years experience in fluorescence confocal imaging, with preference in multi-photon microscopy.  Experience in image analysis with working and programming knowledge of ImageJ or Matlab will be an advantage.

 

The successful candidate will join the Imaging Unit of BRFAA (http://www.bioacademy.gr/Faculty/core.php?cr=17). He/she will collaborate with members of the institute in imaging projects and (i) advise on the best usage of a new multi-photon confocal microscope and a stereology image analysis workstation, (ii) provide training in these techniques (iii) advise and design algorithms for data analysis, and interpretation.

 

The position is available for a duration of 18 months.  Interested candidates should send their CV, including contact details for 3 referees, and a letter of intent to: [hidden email], [hidden email], and [hidden email].

*********************************

Stamatis Pagakis Ph.D.

Biological Imaging Unit

Biomedical Research Foundation, Academy of Athens

Soranou Efessiou 4, Athens 115 27 - Greece

M:     [phone]                 

W:     [phone]

FAX: [phone]

http://www.bioacademy.gr/Faculty/core.php?cr=17